OPKO Health to Expand Latin American Presence with Acquisition of Uruguayan Pharmaceutical Company

OPKO Health (Ireland)

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December 16, 2013 8:30am EST

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Acquisition of Laboratorio Arama de Uruguay Limitada Will Add to

Growing South American Presence in Important Mercosur Market

Provides Platform for Near-Term Launch of 4Kscore ™ Prostate

Cancer Test and Enhances Commercial Synergies Amongst OPKO Units

MIAMI--(BUSINESS WIRE)--

OPKO Health, Inc. (NYSE: OPK )

has entered into an agreement to acquire Laboratorio Arama de Uruguay

Limitada (“Arama”). Domiciled in Montevideo, Uruguay, Arama will add to

our growing South American presence in the important Mercosur economic

region while further complementing our business activities in Chile,

Mexico and Brazil. The transaction is expected to close in January 2014.

This purchase is consistent with OPKO’s strategy of acquiring small,

growing pharmaceutical companies which provide a platform to

commercialize existing and future OPKO products while enhancing

commercial synergies among our various units.

“We continue to broaden our commercial prospects through investments

that complement our existing businesses and bolster the global reach of

our robust product pipeline,” said Phillip Frost, M.D., Chairman and CEO

of OPKO. "This acquisition will allow OPKO to establish a footprint in

Uruguay and facilitate future sales and commercial expansion into

neighboring Argentina. In the near term, Arama provides another platform

for the commercialization of our 4Kscore ™, a novel panel of

biomarkers and associated algorithm to more accurately detect and grade

possible prostate cancers.”

About OPKO Health, Inc.

OPKO is a multinational biopharmaceutical and diagnostics company that

seeks to establish industry leading positions in large, rapidly growing

markets by leveraging its discovery, development and commercialization

expertise and novel and proprietary technologies.

This press release contains "forward-looking statements," as that

term is defined under the Private Securities Litigation Reform Act of

1995 (PSLRA), which statements may be identified by words such as

"expects," "plans," "projects," "will," "may," "anticipates,"

"believes," "should," "intends," "estimates," and other words of similar

meaning, including statements regarding the benefits and synergies

resulting from the acquisition of Arama, including whether Arama will

provide a platform to commercialize existing and future OPKO products

and enhance synergies among our various units, whether OPKO will be able

to broaden its commercial prospects and global reach and expand into

Argentina, whether OPKO's portfolio of products in Latin America will

grow, whether Arama will provide a commercial platform that supports the

near-term launch of OPKO's 4Kscore™ the timing for the launch of the

4Kscore™, the potential benefits of the 4Kscore™, the ability to more

accurately detect and grade possible prostate cancers, whether OPKO or

Arama will be able to successfully commercialize the 4Kscore™, as well

as other non-historical statements about our expectations, beliefs or

intentions regarding our business, technologies and products, financial

condition, strategies or prospects. Many factors could cause our actual

activities or results to differ materially from the activities and

results anticipated in forward-looking statements. These factors include

those described in our filings with the Securities and Exchange

Commission, as well as risks inherent in funding, developing and

obtaining regulatory approvals of new, commercially-viable and

competitive products and treatments. In addition, forward-looking

statements may also be adversely affected by general market factors,

competitive product development, product availability, federal and state

regulations and legislation, the regulatory process for new products and

indications, manufacturing issues that may arise, patent positions and

litigation, among other factors. The forward-looking statements

contained in this press release speak only as of the date the statements

were made, and we do not undertake any obligation to update

forward-looking statements. We intend that all forward-looking

statements be subject to the safe-harbor provisions of the PSLRA.

OPKO Health, Inc.

Steven D. Rubin or Juan F. Rodriguez, 305-575-4100

Source: OPKO Health, Inc.

Released December 16, 2013

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