OPKO Health Announces Completion of Public Offering of Common Stock

OPKO Health (Ireland)

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March 14, 2011 12:20pm EDT

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MIAMI--(BUSINESS WIRE)--

OPKO Health, Inc. (NYSE Amex:OPK) today announced the completion of a

public offering of 27,000,000 shares of its common stock at a price to

the public of $3.75 per share, before underwriting discounts and

commissions. The Company has granted the underwriters a 30-day option to

purchase up to an additional 4,050,000 shares of common stock. All of

the shares were offered by the Company.

The Company anticipates using the net proceeds of the offering for

general corporate purposes, including research and development expenses,

clinical trials, acquisitions of new technologies or businesses, and

other business opportunities.

Jefferies & Company, Inc. and J.P. Morgan Securities LLC acted as joint

book-running managers for the offering. UBS Investment Bank and Lazard

Capital Markets LLC acted as co-lead managers for the offering and

Ladenburg Thalmann & Co. Inc., a subsidiary of Ladenburg Thalmann

Financial Services Inc. (NYSE Amex:LTS), acted as co-manager for the

offering.

The securities described above were offered by the Company pursuant to a

shelf registration statement previously filed with and declared

effective by the U.S. Securities and Exchange Commission (the "SEC"). A

final prospectus supplement related to the offering has been filed with

the SEC and is available on the SEC's website located at http://www.sec.gov .

Copies of the final prospectus supplement related to these securities

may be obtained from the Equity Syndicate Prospectus Department,

Jefferies & Company, Inc., 520 Madison Avenue, 12th Floor, New York, NY,

10022, at 877-547-6340, and at Prospectus_Department@Jefferies.com ,

or from J.P. Morgan Securities LLC, c/o Broadridge Financial Solutions,

1155 Long Island Avenue, Edgewood, New York 11717 or by calling

1-866-803-9204.

This press release shall not constitute an offer to sell or the

solicitation of an offer to buy these securities, nor shall there be any

sale of these securities in any state or other jurisdiction in which

such offer, solicitation or sale would be unlawful prior to the

registration or qualification under the securities laws of any such

state or other jurisdiction.

About OPKO Health, Inc.

We are a multi-national pharmaceutical and diagnostics company that

seeks to establish industry-leading positions in large and rapidly

growing medical markets by leveraging our discovery, development and

commercialization expertise and our novel and proprietary technologies.

Our current focus is on conditions with major unmet medical needs

including neurological disorders, infectious diseases, oncology and

ophthalmologic diseases.

Certain of the statements made in this press release are

"forward-looking statements," as that term is defined under the Private

Securities Litigation Reform Act of 1995 (PSLRA), which statements may

be identified by words such as "expects," "plans," "projects," "will,"

"may," "anticipates," "believes," "should," "could," "intends,"

"estimates," and other words of similar meaning, including statements

regarding our offering of shares of common stock and the expected use of

proceeds of such offering. Many factors, including those described in

our filings with the Securities and Exchange Commission, could cause

actual results or developments to differ materially from those projected

or implied in these forward-looking statements. In addition,

forward-looking statements may also be adversely affected by risks

inherent in funding, developing and obtaining regulatory approvals of

new, commercially-viable and competitive products and treatments,

general market factors, competitive product development, product

availability, federal and state regulations and legislation, the

regulatory process for new products and indications, manufacturing

issues that may arise, patent positions and litigation, among other

factors. The Company will continue to need significant amounts of

additional capital to fund its operations and may be unable to raise

capital when needed, which would force the Company to delay, reduce the

scope of or eliminate one or more of its development programs.

Additional risks and uncertainties relating to the offering, the Company

and its business can be found under the heading "Risk Factors" in the

final prospectus supplement related to the offering filed with the

Securities and Exchange Commission. The Company disclaims any intention

or obligation to update or revise any forward-looking statements,

whether as a result of new information, future events or otherwise.

Source: OPKO Health, Inc.

Released March 14, 2011

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