OPKO Completes Acquisition of Bio-Reference Laboratories

OPKO Health (Ireland)

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August 20, 2015 10:42am EDT

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MIAMI--(BUSINESS WIRE)--

OPKO Health, Inc. (NYSE: OPK) and Bio-Reference Laboratories, Inc.

(NASDAQ: BRLI) today announced the completion of the acquisition of

Bio-Reference by OPKO. Shareholders of Bio-Reference will receive 2.75

shares of OPKO common stock for each share of Bio-Reference common stock.

"The acquisition of Bio-Reference is important for OPKO," commented Dr.

Phillip Frost, OPKO's Chairman and Chief Executive Officer. “For almost

thirty years Dr. Grodman and his team at Bio-Reference Laboratories have

produced a record of innovation and organic growth while building

cutting edge diagnostic franchises in Women’s Health, Cancer, and

Genetics. Bio-Reference’s national infrastructure, reach and extensive

payer network will be invaluable to the adoption of OPKO’s 4Kscore® test

by physicians and patients across the country. However, even more

strategic is the company’s leadership position around the world in

diagnostic sequencing services for rare disorders through its GeneDx

business unit and its emerging cost effective tumor sequencing services

through GenPath Oncology. These assets will be of great value in the

process of drug discovery and development. We look forward to working

with Dr. Grodman and his superb team to build on the great foundation

they have created.”

Dr. Grodman added, “The relationship between therapeutics and

diagnostics has always been assumed; through this acquisition it is our

goal to provide the roadmap on how to fulfill that promise. Under the

leadership of Dr. Frost, who has been an unquestioned leader in seeing

the clinical relevance of new therapeutics, we will dedicate ourselves

to leveraging all the capabilities of Bio-Reference, including our

leadership position in genomics and sequencing services, to bring this

vision to fruition.”

ABOUT OPKO HEALTH, INC.

OPKO is a multinational biopharmaceutical and diagnostics company that

seeks to establish industry-leading positions in large, rapidly growing

markets by leveraging its discovery, development and commercialization

expertise and novel and proprietary technologies. For more information,

visit http://www.opko.com .

ABOUT BIO-REFERENCE LABORATORIES, INC.

Bio-Reference Laboratories is one of the largest and fastest growing

full service diagnostic laboratories in the world, providing clinical

testing services to physician offices, clinics, hospitals, long term

care facilities and employers while also advancing drug discovery and

development with disease foundations, academic and pharmaceutical

partners. Bio-Reference’s comprehensive testing capabilities and

expertise spans molecular diagnostics, anatomical pathology, women's

health, oncology and rare disease genetics. Bio-Reference Laboratories,

and its subsidiaries, has an international presence in more than 50

countries. For more information, visit www.bioreference.com .

SAFE HARBOR STATEMENT

This press release contains "forward-looking statements," as that

term is defined under the Private Securities Litigation Reform Act of

1995 (PSLRA), which statements may be identified by words such as

"expects," "plans," "projects," "will," "may," "anticipates,"

"believes," "should," "intends," "estimates," and other words of similar

meaning, including statements regarding expected benefits of the merger

with Bio-Reference, that its array of genomics data will prove valuable

in enhancing drug discovery and clinical trial programs, whether access

to Bio-Reference’s commercial organization will expedite adoption of the

4Kscore test by physicians and patients and accelerate timelines for

reimbursement of the test by payers, as well as other non-historical

statements about our expectations, beliefs or intentions regarding our

business, technologies and products, financial condition, strategies or

prospects. Many factors could cause our actual activities or results to

differ materially from the activities and results anticipated in

forward-looking statements. These factors include those described in our

filings with the Securities and Exchange Commission, as well as the

risks inherent in funding, developing and obtaining regulatory approvals

of new, commercially-viable and competitive products and treatments. In

addition, forward-looking statements may also be adversely affected by

general market factors, competitive product development, product

availability, federal and state regulations and legislation, challenges

relating to integration of Bio-Reference, the regulatory process for new

products and indications, manufacturing issues that may arise, patent

positions and litigation, among other factors. The forward-looking

statements contained in this press release speak only as of the date the

statements were made, and we do not undertake any obligation to update

forward-looking statements. We intend that all forward-looking

statements be subject to the safe-harbor provisions of the PSLRA.

View source version on businesswire.com: http://www.businesswire.com/news/home/20150820005792/en/

OPKO Health, Inc.

Steven D. Rubin or Adam Logal,

or

Media Contacts

Rooney &

Associates

Terry Rooney, 212-223-0689

Marion Janic, 212-223-4017

Source: OPKO Health, Inc.

Released August 20, 2015

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